Lipid Nanodiscs Market to Reach Valuation of USD 1.7 Billion by 2028 – Growing Integration of PhosphoLipid Nanodiscs Drives the Market

In terms of revenue, the Global Lipid Nanodiscs Market is expected to reach USD 1.7 Billion by 2028, growing at a CAGR (Compound Annual Growth Rate) of 7.40% from 2022 to 2028.

The market for Lipid Nanodiscs is anticipated to increase throughout the projected period. This market's expansion is attributable to the rising demand for Lipid Nanodiscs in the medical and pharmaceutical fields. Artificial lipoproteins called Lipid Nanodiscs are employed as membrane scaffolds for investigating various membrane proteins. They offer a more medically appropriate environment than conventional techniques like detergent solubilization. They can also easily be made in huge quantities and are biocompatible. The growing need for customized treatment, the rising incidence of chronic diseases, and the expanding application of Lipid Nanodiscs in drug delivery & vaccine development are the main factors driving the growth of the Lipid Nanodiscs market.

Key Highlights from the Report

• Among Types, the Membrane Scaffold Protein (MSP) Nanodiscs market segment is anticipated to dominate the Lipid Nanodiscs market with the largest market share in the forecast period due to the best environment for augmented solubility.
• By Applications, the Cancer market segment accounted for the highest CAGR during the forecast period. Due to their improved anisotropy and myriad functionalization options, nano-formulations like Nanodisc platforms have demonstrated impressive potential for targeted drug delivery with greater effectiveness than somatic cancer vaccines.
• In terms of region, North America held the significant market share and is expected to be the most lucrative market during the forecast period. This is because numerous biotechnology start-ups are resolving problems with nanodisc platforms in the region, increasing research and development activity, increasing the number of critical pharmaceutical businesses, and so on.

Market Dynamics

Growing demand for phosphoLipid Nanodiscs, which creates a membrane environment similar to a native cell and facilitates the manufacture of physiologically active folded forms of integral membrane proteins, is anticipated to drive market revenue growth. In addition, these phospho-lipid bilayer nanodiscs have attracted the scientific community's interest in stable and programmable membrane mimics for studying membrane proteins. Another element projected to contribute to the market revenue growth is the expanding advantages of Nanodisc technology over traditional integral membrane proteins for the production of commercial pharmaceutical medications. Because they are essential for many biological functions, such as signal transmission, transport, and the activity of enzymes in diverse metabolic pathways, membrane proteins are excellent prospects for developing novel therapeutics.

Nanodiscs can be manufactured in sizes ranging from 16 nm to a maximum of 90 nm because of recent advances in nanodisc engineering, such as covalently circularised nanodiscs (cND) and DNA corralled nanodiscs (DCND). The development of cNDs and DCNDs has made it possible to create very large nanodiscs, expanding the scope of applications for this technology beyond the study of the structural biology of small membrane proteins to those of large membrane protein complexes and virus membrane interactions. For example, with the help of large nanodiscs, researchers can study how viruses interact with membranes in various ways, addressing questions about the mechanism of membrane penetration, the stages of virus particle breakdown, virus conformations, and the regulatory functions of host cell surface receptors. In addition, large nanodiscs can be further developed to produce asymmetric nanodiscs that more closely resemble membranes, which will aid researchers in understanding biological processes like membrane and vesicular fusion. This will create lucrative opportunities for the market during the forecast period.

The main factors limiting the growth of the Lipid Nanodiscs market are the lack of FDA approval for some applications, such as cancer therapy, and the difficulty of manufacturing Lipid Nanodiscs with high payload capacity.

North America Lipid Nanodiscs market is projected to view a remarkable increase with a significant growth rate over the analysis period. Increased spending on R&D, new biotechnology start-ups using nanodisc platforms, the presence of numerous research organizations, and collaborations with crucial pharmaceutical corporations for nanodisc technologies are the main drivers of market expansion in this sector. Nanodisc technologies are being made available thanks to the presence of various research groups and partnerships with significant pharmaceutical corporations. In addition, government-funded research programs, an increase in the number of studies using nanodisc technology, and increased government financing for R&D activities are some of the major factors boosting market expansion in the region.

The Global Lipid Nanodiscs Market is Segmented as follows

• Types
  • Membrane Scaffold Protein (MSP) Nanodiscs
  • Synthetic Nanodiscs
• Applications
  • Cancer
  • Neurodegenerative Diseases
  • Infectious Disease
  • Drug Development & Discovery
  • Other Applications
• Region
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

List of the Key Players of the Global Lipid Nanodiscs Market is

Merck KGaA (Germany), Cube Biotech (Germany), Anatrace Products LLC (U.S.), ideXLab (France), MEMPRO USA LTD (U.S.), Nano Temper (U.S.)

The Global Lipid Nanodiscs Market Scope can be Tabulated as below