Migraine Drugs Market
Migraine Drugs Market - Global Industry Assessment & Forecast
Segments Covered
- By Treatment Acute, Preventive
- By Therapeutic class CGRP Monoclonal Antibodies, CGRP Small Molecule Antagonists, Acetylcholine inhibitors/ neurotoxins, Triptans, Ditans, Ergot alkaloids, NSAIDs
- By Route of Administration Oral, Injectable, Others
- By Age group Pediatric, Adult, Geriatric
- By Availability prescription drugs, Over-the-Counter (OTC) drugs
- By Region North America, Europe, Asia Pacific, Latin America, Middle East & Africa
Snapshot
Base Year: | 2023 |
Forecast Years: | 2024 - 2032 |
Historical Years: | 2018 - 2022 |
Revenue 2023: | USD 6.37 Billion |
Revenue 2032: | USD 21.59 Billion |
Revenue CAGR (2024 - 2032): | 11.75% |
Fastest Growing Region (2024 - 2032) | Asia Pacfic |
Largest Region (2023): | North America |
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The global Migraine Drugs Market is valued at USD 6.37 Billion in 2024 and is projected to reach a value of USD 21.59 Billion by 2035 at a CAGR (Compound Annual Growth Rate) of 11.75% between 2025 and 2035.
Migraine is a medical condition characterized by severe headaches often accompanied by symptoms such as nausea, sensitivity to smells, and other sensory disturbances. These headaches typically affect one side of the head, with each migraine episode varying in duration and intensity. Medications in this market are specifically designed to manage the headaches and associated symptoms caused by migraines. The rising prevalence of migraines worldwide serves as a significant factor drives the growth of the Migraine Drugs market. The rise in Research and Development in pharmaceutical companies for enhancing different types of migraine drugs, and tentative approval of pipeline candidates accelerate the Migraine Drugs market industry.
Key Highlights
- In 2024, based on the Treatment, the Acute category accounted largest share of 62.70% in Migraine Drugs market industry
- Based on the Therapeutic class, the CGRP monoclonal antibodies category accounted for significant market share of 58.50% in Migraine Drugs market in 2024
- In 2024, based on the Route of Administration, the Injectable category accounted largest share in Migraine Drugs market industry
- In 2024, based on the Age group, the Adult category accounted largest share of 53.80% in Migraine Drugs market industry
- Based on the Availability, the Prescription Drugs category accounted for significant market share of 79.40% in Migraine Drugs market in 2024
- North America dominated the Migraine Drugs market industry with largest market share of 41.30% in 2024
- Europe region is anticipated to grow at the highest CAGR during the forecast period
Migraine Drugs Market Size, 2023 To 2032 (USD Billion)
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Treatment Overview
The Treatment segment is divided into Acute and Preventive. The Acute segment held the largest share of 62.70% in the Migraine Drugs market industry.
Acute treatment involves a range of medications and approaches aimed at relieving symptoms during a migraine episode. Key drugs in this category include Rimegepant, Ubrogepant, and Zavegepant. To aid patients experiencing acute migraines, several companies are implementing initiatives such as providing medications at no cost. The segment is witnessing growth due to increasing patient awareness, improved access to fast-acting treatments, and initiatives by pharmaceutical companies to support patients, such as free medication programs and affordability schemes. Ongoing advancements in drug formulations and delivery methods further strengthen the acute segment, making it a vital component of the Migraine Drugs market industry.
The preventive segment is anticipated to growing at the fastest CAGR over the forecast period in Migraine Drugs market. Preventive therapies include a range of drug classes such as beta-blockers, calcium channel blockers, antidepressants, anticonvulsants, and more recently, CGRP (calcitonin gene-related peptide) inhibitors like erenumab, fremanezumab, and galcanezumab. For instance, in April 2023, AbbVie announced that the U.S. Food and Drug Administration (FDA) has approved expanding the indication of QULIPTA® (atogepant) for the preventive treatment of migraine in adults. The approval makes QULIPTA the first and only oral calcitonin gene-related peptide (CGRP) receptor antagonist approved to prevent episodic and chronic migraine. People living with chronic migraine experience headaches for 15 or more days per month, with at least eight of those days associated with migraine.
Therapeutic Class Overview
The Therapeutic class segment is divided into CGRP Monoclonal Antibodies, CGRP Small Molecule Antagonists, Acetylcholine inhibitors/ neurotoxins, Triptans, Ditans, Ergot alkaloids, and NSAIDs. The CGRP monoclonal antibodies segment held the largest share of 58.50% in the Migraine Drugs market industry.
- CGRP Monoclonal Antibodies: These are advanced biologic therapies designed to prevent migraines by targeting the calcitonin gene-related peptide (CGRP) or its receptor, which play a crucial role in migraine pathophysiology. Drugs like erenumab, fremanezumab, and galcanezumab fall into this category and are particularly effective for chronic and frequent migraines
- CGRP Small Molecule Antagonists: Also known as gepants, these oral drugs block CGRP activity to alleviate migraine symptoms and prevent attacks. Examples include rimegepant and ubrogepant, offering an alternative for patients who cannot tolerate triptans
- Acetylcholine Inhibitors/Neurotoxins: Treatments like onabotulinumtoxinA (Botox) are used for chronic migraine prevention by inhibiting the release of acetylcholine and relaxing muscles to reduce pain triggers. These are primarily prescribed for patients with chronic, severe migraines
- Triptans: Triptans, such as sumatriptan and zolmitriptan, are widely used for acute migraine treatment. They work by stimulating serotonin receptors, causing the constriction of dilated blood vessels and blocking pain pathways in the brain
- Ditans: A newer class of drugs, such as lasmiditan, that selectively target serotonin 5-HT1F receptors. Ditans provide an option for acute migraine treatment without causing vasoconstriction, making them suitable for patients with cardiovascular risks
- Ergot Alkaloids: Medications like dihydroergotamine act on serotonin receptors to constrict blood vessels and reduce migraine-related pain. Though less commonly used, they remain effective for specific patient groups and refractory migraines
- NSAIDs: Nonsteroidal anti-inflammatory drugs, such as ibuprofen and naproxen, are often used for mild to moderate migraines. They alleviate pain and inflammation, serving as accessible options for early-stage or infrequent migraine attacks
Availability Overview
The Availability segment is divided into prescription drugs and Over-the-Counter (OTC) drugs. The prescription drugs segment held the largest share of 79.40% in the Migraine Drugs market industry.
Prescription drugs are widely used treatment option for managing migraines in Migraine Drugs market. The segment is driven by rising prevalence of migraines globally. As more people are diagnosed with migraines, there is a higher demand for effective medications. The prescription drugs are tailored to address the severity and frequency of migraine attacks and are often a part of personalized treatment plans designed by medical professionals. Their availability through prescriptions ensures that patients receive proper guidance on dosage, potential side effects, and interactions with other medications, improving treatment outcomes.
Regional Overview
In 2024, the Migraine Drugs market size of the North America is USD 2.63 Billion.
North America Migraine Drugs market industry is driven by a high prevalence of migraine cases, advanced healthcare infrastructure, and strong awareness about available treatments. For instance, in July 2024, 1 in 5 Americans suffers from a mental illness (NIMH), with anxiety disorders being the most prevalent, impacting 42.5 million people, as reported by Mental Health America. Alarmingly, symptoms of mental illnesses often begin by age 14, highlighting the need for early intervention (National Alliance on Mental Illness). Additionally, the growing focus on personalized medicine and the availability of advanced diagnostic tools have further enhanced the adoption of migraine drugs in the region. Continuous efforts by companies to introduce innovative products and patient support programs are also contributing to the growth of the Migraine Drugs market in industry.
U.S. Migraine Drugs Market Analysis
The U.S. Migraine Drugs market is driven by a high prevalence of migraines, advanced healthcare infrastructure, and strong awareness of treatment options. A substantial portion of the population experiences migraines, prompting significant demand for effective therapeutic solutions. For Instance, in March 2023, The U.S. Food and Drug Administration on Friday approved Pfizer Inc's, opens new tab nasal spray for migraine, giving patients access to a potentially fast-acting pain-relief option for headaches. The U.S. Migraine Drugs market benefits from extensive research and development activities, leading to the introduction of advanced drugs such as CGRP inhibitors and gepants, which have transformed migraine management.
Europe Migraine Drugs Market Analysis
The Europe Migraine Drugs market size is expected to account for a substantial share driven by factors such as advantageous reimbursement regulations and non-government supportive services that help raise knowledge about migraine and its drugs treatment choices. In region, countries like Germany, the United Kingdom, and France are key contributors, benefiting from advanced healthcare systems and robust pharmaceutical industries. European Migraine Drugs market is driven by rising prevalence of migraines, coupled with improved access to specialized treatments such as CGRP inhibitors. Additionally, ongoing research and clinical trials in Europe are advancing the development of new drugs, while collaborations between pharmaceutical companies and research institutions are expanding the pipeline of treatment options.
Migraine Drugs Market Industry Trends
- Rising awareness and early diagnosis of migraine disorders: As awareness about the symptoms and impact of migraines increases, more individuals are seeking medical attention, leading to earlier diagnosis and treatment. Early identification of migraine disorders allows for more effective management and the timely initiation of appropriate therapies, which can reduce the frequency and severity of attacks
- Advancements in biologic therapies and novel drug delivery methods: Biologic therapies, particularly CGRP inhibitors, represent a major breakthrough in migraine treatment. These therapies specifically target the calcitonin gene-related peptide (CGRP), a protein involved in migraine pathophysiology, offering a more targeted and effective approach compared to traditional treatments
- Rising demand for non-invasive and minimally disruptive migraine treatments: As patients increasingly seek alternatives to traditional treatments, there is growing interest in therapies that provide relief without the need for injections, extensive medical procedures, or extended recovery times. Non-invasive treatments, such as oral medications, nasal sprays, and transdermal patches, are becoming more popular due to their convenience and ease of use
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Market Dynamics
Improvements in Drug Development
Improvements in drug development are significantly advancing the Migraine Drugs market industry. The introduction of novel drug categories like CGRP inhibitors and gepants has revolutionized treatment by offering targeted mechanisms that effectively reduce the severity and frequency of migraines. These innovations are driving continued progress and Migraine Drugs market growth. Ongoing research into migraine pathophysiology is also contributing to the development of advanced therapies, while a deeper understanding of the genetic and molecular basis of migraines is enabling the creation of personalized treatments. This combination of scientific breakthroughs is enhancing treatment options and improving outcomes for migraine sufferers.
Rising government regulations for migraine drugs
The rising government regulations for migraine drugs, increased adoption of innovative drugs classes, and increasing FDA approvals are the major factors driving the Migraine Drugs market growth over the forecast period. For instance, in September 2023, AbbVie announced that the U.S. Food and Drug Administration (FDA) approved QULIPTAâ„¢ (atogepant) for the preventive treatment of episodic migraine in adults. QULIPTA is the first and only oral calcitonin gene-related peptide (CGRP) receptor antagonist (gepant) specifically developed for the preventive treatment of migraine.
Competitive Landscape
The Migraine Drugs market report is characterized by the presence of both established players and emerging companies, each strive for market share through product innovation, strategic partnerships, and geographic expansion. Industry giants like AbbVie Inc, Amgen Inc, Teva Pharmaceuticals Industries, GSK Plc, Eli Lily and Company, Pfizer Inc, Bausch Health Companies Inc, Gensco Pharma, Impel Pharmaceuticals Inc, Tonix Medicines Inc, Currax Pharmaceuticals LLC. Additionally, Emerging companies are focusing on the development of non-invasive treatments and novel drug delivery systems, further intensifying competition. Strategic collaborations, mergers, and acquisitions are also common as companies seek to expand their product portfolios and improve Migraine Drugs market access.
The key players in the global Migraine Drugs market industry report include - AbbVie Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., GSK plc, Eli Lilly and Company, Pfizer Inc., Bausch Health Companies Inc., Gensco Pharma, Impel Pharmaceuticals Inc., Tonix Medicines, Inc., Currax Pharmaceuticals LLC., Lundbeck among others.
Recent Market Developments
Amazon Pharmacy now provides home delivery of select diabetes, obesity, and migraine medications to LillyDirect patients
- In March 2024, Lilly has selected Amazon Pharmacy as a dispensing pharmacy option, allowing patients to receive fast, free delivery of medications and 24/7 access to clinical pharmacists
Organon & Lilly Enter Commercialization Agreement in Europe for Two Migraine Medicines
- In December 2023, Organon, a global healthcare company with a focus on women’s health, announced an agreement with Eli Lilly and Company (Lilly) to become the sole distributor and promoter for the migraine medicines Emgality® (galcanezumab) and RAYVOW™(lasmiditan) in Europe
The global Migraine Drugs market can be categorized as Treatment, Therapeutics Class, Route of Administration, Age Group, Availability, and Region.
Parameter | Details |
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Segments Covered |
By Treatment
By Therapeutic class
By Route of Administration
By Age group
By Availability
By Region
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Regions & Countries Covered |
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Companies Covered |
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Report Coverage | Market growth drivers, restraints, opportunities, Porter’s five forces analysis, PEST analysis, value chain analysis, regulatory landscape, technology landscape, patent analysis, market attractiveness analysis by segments and North America, company market share analysis, and COVID-19 impact analysis |
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FAQ
Frequently Asked Question
What is the global demand for Migraine Drugs in terms of revenue?
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The global Migraine Drugs valued at USD 6.37 Billion in 2023 and is expected to reach USD 21.59 Billion in 2032 growing at a CAGR of 11.75%.
Which are the prominent players in the market?
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The prominent players in the market are AbbVie Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., GSK plc, Eli Lilly and Company, Pfizer Inc., Bausch Health Companies Inc., Gensco Pharma, Impel Pharmaceuticals Inc., Tonix Medicines, Inc., Currax Pharmaceuticals LLC., Lundbeck.
At what CAGR is the market projected to grow within the forecast period?
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The market is project to grow at a CAGR of 11.75% between 2024 and 2032.
What are the driving factors fueling the growth of the market.
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The driving factors of the Migraine Drugs include
Which region accounted for the largest share in the market?
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North America was the leading regional segment of the Migraine Drugs in 2023.